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Vertex says drug reduced marker of kidney disease in late-stage trial

The biotech company is in a three-way race with Otsuka and Vera Therapeutics to treat the condition, called IgA nephropathy.

BusinessBy Catherine ChenMarch 9, 20261 min read

Last updated: April 1, 2026, 12:56 PM

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Vertex says drug reduced marker of kidney disease in late-stage trial

Company is in a three-way race to treat IgA nephropathy

Jason Mast is a general assignment reporter at STAT focused on the science behind new medicines and the systems and people that decide whether that science ever reaches patients. You can reach Jason on Signal at JasonMast.05.

Vertex said Monday that a drug it secured as part of a $4.9 billion acquisition successfully reduced by half a key marker of a kidney disease known as IgA nephropathy.

The results, from a Phase 3 trial, match data from a study of Otsuka’s recently approved Voyxact and are numerically superior to data released last year by Vera Therapeutics.

All three companies have been racing to treat a disease that affects 330,000 people across the U.S. and Europe, according to Vertex’s estimates, putting many at risk of developing end-stage renal disease. Analysts have projected Vertex’s drug could eventually bring in $4 billion or more in annual sales.

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Catherine Chen

Financial Correspondent

Catherine Chen covers finance, Wall Street, and the global economy with a focus on business strategy. A former financial analyst turned journalist, she translates complex economic data into clear, actionable reporting. Her coverage spans Federal Reserve policy, cryptocurrency markets, and international trade.

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