Multidimensional profiling of heterogeneity in supratentorial ependymomas - Nature
Individual supratentorial ependymoma tumour subgroups have two distinct progenitor-like cell states—neuroepithelial-like and embryonic-like—that are reminiscent of early human brain development and diverge in the extent of their neuronal or ependymal dif…
Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor - Nature
Marburgvirus glycoprotein binds to the endosomal receptor NPC1 in a distinct orientation with higher affinity compared with Ebola virus glycoprotein, accompanied by fusion-relevant rearrangements, enabling more efficient viral entry.
Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor
Marburgviruses (MBVs) cause severe haemorrhagic fever with higher fatality rates than Ebola virus (EBOV)1–4. Here we show that the MBV glycoprotein (GP) mediates viral entry more efficiently than EBOV GP. Using cryo-EM, we determined structures of MBV GP in three states: (1) unbound; (2) bound to it
Undigested fruit sugar is linked to increased anxiety and inflammation
When the digestive system fails to absorb fructose, the lingering sugar disrupts the gut microbiome. A recent study reveals this bacterial shift sparks low-grade, body-wide inflammation that can alter brain immune cells and increase anxiety.
Woman with Stage 4 cancer has 'no evidence of disease' after life-changing transplant
A woman with cancer that spread to her liver is getting a second chance at life after receiving an organ transplant from a living donor.
Memory loss is fuelled by gut microbes in ageing mice - Nature
If confirmed in people, the finding might lead to gut-targeted therapies that could reverse cognitive decline.
These kinds of relationships are literally aging you faster
According to the findings of a study conducted in Indiana, these types of people have the potential to speed up cellular aging by roughly 1.5%.
3 great supplements for your heart
Nearly half of all US adults have some form of cardiovascular disease, the leading cause of death nationwide. The Post spoke to a cardiologist who broke down three supplements that can boost heart health — and four others that may put it at risk.
Cardiologists Say This Simple Habit Lowers Your Risk of Heart Disease - AOL.com
The Type Of Fish That Restaurant Workers Rarely Order, According To Reddit
People can be particularly picky when it comes to fish, but even restaurant workers don't want to eat one type. Find out which fish to avoid ordering.
Intestinal interoceptive dysfunction drives age-associated cognitive decline - Nature
Age-related microbiome changes increase medium-chain fatty acid-producing bacteria, driving GPR84-mediated myeloid inflammation, impaired vagal signalling and hippocampal dysfunction; targeting this gut–brain pathway restores memory in aged mice.
Signs of throat cancer caused by oral sex after Michael Douglas shared what he noticed first
The actor said that one particular symptom stood out to him for a long period of time
Significant Heart Disease Risk Can Be Detected from Routine Mammograms Using AI - Up to 70% Greater
The team used AI to analyze the amount of calcium deposit in the arteries of the breast tissue, known to be a risk factor for heart disease.
What to know about CDC’s new polio alert
Polio is not endemic in the United States, but the disease is circulating in 30 other countries now. A doctor explains how to protect against polio when traveling.
Insomnia Can Be an Early Alzheimer's Warning Sign. New Research Explains Why.
Problems with sleep often show up much earlier than more recognizable symptoms in people who develop Alzheimer's disease, but why? A new study offers a major clue, tied to the toxic build-up of tau protein in the brain that accompanies Alzheimer's.
Measles case confirmed in Washtenaw County -- Here’s a list of exposure sites
A measles case has been confirmed in Washtenaw County, and health officials are notifying the public about possible exposure at multiple locations.
A Pill for Sleep Apnea? Clinical Trial Yields Promising Results - Gizmodo
An old anti-seizure drug might also work to reduce apnea episodes, recent trial data has shown.
I was diagnosed with aggressive cancer and told I had a year to live... three years later I am cancer free thanks to my diet and supplement regimen
Kimberly was told she had one year to live after being diagnosed with aggressive brain cancer. Three years later, after declining further medical treatment and enacting lifestyle changes, she is cancer-free.
'Most Loving' Mom, 33, Died After Hospital Gave Her Wrong Antibiotics, Leaving 'Huge Void' in Her Family
Aleisha Rochester's mom said "the hardest thing" to accept is that she will never see her son "grow up and celebrate milestones in life"
Scientists revive activity in frozen mouse brains for the first time - Nature
‘Cryosleep’ remains the preserve of science fiction, but researchers are getting closer to restoring brain function after deep freezing.
Key signs that you are overdosing on Vitamin D following warning - ladbible.com
Exceeding the daily recommended dose of vitamin D can do more harm than good, according to the NHS, and it can result in some unfortunate symptoms.
Weight loss jab ‘may carry higher risk of sudden sight loss’ as new warning issued
Wegovy is approved on the NHS to help people lose weight in higher doses
VA Study: Ozempic, Other GLP-1 Drugs May Fight Addiction Across Every Major Substance
For the more than 48 million Americans with substance use disorders, including a disproportionate share of veterans, GLP-1 drugs are not yet an approved addiction treatment. But the evidence base is growing, and it is coming from the VA.
Rabid Raccoon In Granby, Police Issue Alert
Police say a raccoon found sick on Fawn Drive tested positive for rabies, prompting a reminder to avoid wildlife acting abnormally.